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This study was undertaken to examine the possibility of association between pathogenicity of Genus Bacillus and the induction of superoxide dismutase(SOD) activity.. In this study, pathogenic 8, anthracis ATCC 14578, vaccine strains; Army No. 2 and Sterne, and other 4 strains of Bacillus gecies were included. The induction of SOD of Genus Bacillus was tested after cultivation by candle jar method.
The results are summarized as follows:
1. Induction of total SOD activities was observed in pathogenic B. anthracis ATCC 14578 when cultured under reduced oxygen tension(candle jar method). (p)0.057
2. Nonpathogenic strains, B. anthracis Army No. 2 and Sterne, and other 4 strains of related Bacillus species, were not observed the induction of SOD acttvit.v.
:. In the induction experiments, B. anthracis ATCC 14578 showed significant increment of Mn SOD activity. But, other nonpathogenic strains failed to show statistically significant increase of Mn-SOD activity.
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- These results suggest that the pathogenicity of Genus Bacillus may be associated with inducible activity- of SOD.
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